Infectious Agammaglobulinemia: Transmission of Immunodeficiency with Grafts of Agammaglobulinemic Cells

نویسندگان

  • R. Michael Blaese
  • Paul L. Weiden
  • Irma Koski
  • Nancy Dooley
چکیده

Agammaglobulinemia induced in chickens by surgical bursectomy and irradiation at hatching is transmissible at 4 mo of age to sublethally irradiated normal chickens by bone marrow transplantation. The immunodeficiency which develops in the recipients persists for life and is characterized by inability to produce antibody and by progressive loss of detectable serum IgM and IgG.

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عنوان ژورنال:
  • The Journal of Experimental Medicine

دوره 140  شماره 

صفحات  -

تاریخ انتشار 1974